Anthony Joshua will defend his three world titles against Kubrat Pulev in front of 1,000 fans at Wembley Arena next weekend.
The heavyweight champion will return to the ring for the first time since his revenge mission against Andy Ruir Jr last December.
And he will be the first British world champion to fight in front of a crowd since the coronavirus pandemic struck in March.
Promoter Eddie Hearn said: “I can’t tell you how happy I am to see fans returning to our live boxing events.
“Whilst the team have done an incredible job over the last 10 months we live and breathe through the energy and atmosphere that a live crowd generates.
“It’s so fitting that they can return for an AJ fight, when through the last few years he has broken all kinds of attendance records in the U.K. and beyond. This is such a positive move for boxing and all sport. Welcome back!”
Hearn and his Matchroom team have set up a residency at Wembley Arena since October with Joshua completing their stint.
Tickets go on sale on Friday priced between £100 and £1000 and fans will be required to wear face coverings. Groups of fans must also be from the same household.
Joshua and Pulev will headline a card which includes Lawrence Okolie’s world title challenge against former champion Krzysztof Glowacki.
Hughie Fury will take on Mariusz Wach, Martin Bakole faces a crossroads test against Sergey Kuzmin and Souleymane Cissoko faces Kieron Conway.
Joshua must successfully defend his belts if he is to secure a unification clash with fellow world champion Tyson Fury.
Fury, who has been included on the shortlist for the BBC Sports Personality of the Year award, could be ringside at Wembley Arena to watch his rival.